The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2014

Filed:

May. 12, 2011
Applicants:

Dong-ming Shen, Edison, NJ (US);

John S. Debenham, Scotch Plains, NJ (US);

Thomas H. Graham, Scotch Plains, NJ (US);

Matthew J. Clements, Old Bridge, NJ (US);

Yong Zhang, West Windsor, NJ (US);

Inventors:

Dong-Ming Shen, Edison, NJ (US);

John S. Debenham, Scotch Plains, NJ (US);

Thomas H. Graham, Scotch Plains, NJ (US);

Matthew J. Clements, Old Bridge, NJ (US);

Yong Zhang, West Windsor, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/445 (2006.01); A61K 31/40 (2006.01); A61K 31/415 (2006.01); C07D 295/18 (2006.01); C07D 413/12 (2006.01); C07D 211/30 (2006.01); C07D 207/06 (2006.01); C07D 233/61 (2006.01); C07D 205/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the enzymatic activity of PrCP such as abnormal metabolism, including obesity; diabetes; metabolic syndrome; obesity related disorders; and diabetes related disorders.


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