The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2014

Filed:

Sep. 24, 2010
Applicants:

Eiji Kawaminami, Tokyo, JP;

Tatsuhisa Takahashi, Tokyo, JP;

Takatoshi Kanayama, Tokyo, JP;

Yuta Fukuda, Tokyo, JP;

Hiroyuki Kaizawa, Tokyo, JP;

Yutaka Kondoh, Tokyo, JP;

Ryushi Seo, Tokyo, JP;

Kazuyuki Kuramoto, Tokyo, JP;

Kazuhiko Take, Tsukuba, JP;

Kazuyuki Sakamoto, Tokyo, JP;

Inventors:

Eiji Kawaminami, Tokyo, JP;

Tatsuhisa Takahashi, Tokyo, JP;

Takatoshi Kanayama, Tokyo, JP;

Yuta Fukuda, Tokyo, JP;

Hiroyuki Kaizawa, Tokyo, JP;

Yutaka Kondoh, Tokyo, JP;

Ryushi Seo, Tokyo, JP;

Kazuyuki Kuramoto, Tokyo, JP;

Kazuhiko Take, Tsukuba, JP;

Kazuyuki Sakamoto, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/341 (2006.01); A61K 31/381 (2006.01); A61K 31/401 (2006.01); A61K 31/415 (2006.01); C07D 207/34 (2006.01); C07D 213/81 (2006.01); C07D 263/34 (2006.01); C07D 277/56 (2006.01); C07D 307/68 (2006.01); C07D 333/38 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A substituted amide compound is useful as an active ingredient of a pharmaceutical composition, in particular a pharmaceutical composition for treating diseases caused by lysophosphatidic acid (LPA). The compound is of a formula: In this formula, A is an optionally substituted aryl, etc.; B is an optionally substituted 5-membered aromatic hetero ring group; X is a single bond or —(CRR)—; n is 1, 2, 3, or 4; Rand Rare hydrogen, etc.; Yto Yare each CRor N; each Ris hydrogen, etc.; Rand Rare hydrogen, etc.; m is 1, 2, or 3; Ris hydrogen, etc.; and Ris an optionally substituted lower alkyl, etc.


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