The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8669244 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 11, 2014

Filed:

Jun. 30, 2011
Applicants:

Ching-jang Huang, Taipei, TW;

Yueh-hsiung Kuo, Taipei, TW;

Chin Hsu, Taipei, TW;

Inventors:

Ching-Jang Huang, Taipei, TW;

Yueh-Hsiung Kuo, Taipei, TW;

Chin Hsu, Taipei, TW;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/585 (2006.01); A61K 31/56 (2006.01); C07J 71/00 (2006.01); C07J 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a cucurbitane-triterpenoid compound for activating estrogen receptor activity, and a pharmaceutical composition, use and preparation method thereof. The cucurbitane-triterpenoid compound is presented as formula (I): wherein a single bond or a double bond is formed between C5 and C10, and a single bond or a double bond is fromed between C8 and C9; when a single bond is formed between C5 and C10, the Ris oxygen; while a single bond is formed between C8 and C9, Ris carbonyl group (—C═O), methyl hydroxyl group (—CH(OH)), methyl ketone or methyl dimethoxy group (—CH(OCH)); and wherein while Ris oxygen (—O—) and Ris carbonyl group (—C═O) or methyl hydroxyl group (—CH(OH)), a single bond is formed between R(—O—) and C19 of Rsuch that Rand Rare formed tetrahydro-2H-pyran-2-one or hemiacetal ring.


Find Patent Forward Citations

Huang, Ching-Jang. (2014). Cucurbitane-triterpenoid compounds, pharmaceutical composition, use and preparation method thereof (U.S. Patent No. 8669244). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8669244

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