The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Jun. 30, 2011
Ching-jang Huang, Taipei, TW;
Yueh-hsiung Kuo, Taipei, TW;
Chin Hsu, Taipei, TW;
National Taiwan University, Taipei, TW;
Abstract
Disclosed is a cucurbitane-triterpenoid compound for activating estrogen receptor activity, and a pharmaceutical composition, use and preparation method thereof. The cucurbitane-triterpenoid compound is presented as formula (I): wherein a single bond or a double bond is formed between C5 and C10, and a single bond or a double bond is fromed between C8 and C9; when a single bond is formed between C5 and C10, the Ris oxygen; while a single bond is formed between C8 and C9, Ris carbonyl group (—C═O), methyl hydroxyl group (—CH(OH)), methyl ketone or methyl dimethoxy group (—CH(OCH)); and wherein while Ris oxygen (—O—) and Ris carbonyl group (—C═O) or methyl hydroxyl group (—CH(OH)), a single bond is formed between R(—O—) and C19 of Rsuch that Rand Rare formed tetrahydro-2H-pyran-2-one or hemiacetal ring.