The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Nov. 13, 2007
Ivaylo Nikolov Gentschev, Wuerzburg, DE;
Joachim Fensterle, Hoechberg, DE;
Ulf R. Rapp, Wuerzburg, DE;
Werner Goebel, Munich, DE;
Ivaylo Nikolov Gentschev, Wuerzburg, DE;
Joachim Fensterle, Hoechberg, DE;
Ulf R. Rapp, Wuerzburg, DE;
Werner Goebel, Munich, DE;
Zentaris GmbH, Frankfurt am Main, DE;
Abstract
A, or Pseudomonas bacterium that has the following components: (I) a polynucleotide encoding a heterologous antigenic determinant that induces a CTL response against a tumor cell; (II) a polynucleotide encoding a heterologous protein toxin or toxin subunit; and (III) (a) a polynucleotide encoding a transport system that expresses the products of (I) and (II) on the outer surface of the bacterium or that secretes products of (I) and (II) from the bacterium; and (IV) a polynucleotide that activates the expression of one or more of (I). (II), and/Or (III) in the bacterium wherein polynucleotides (I), (II), (III) and (IV) are different from each other and polynucleotides (I), (II) and (III) encode proteins that are different from each other.