The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Aug. 28, 2012
Applicants:
Scott B Hansen, Jupiter, FL (US);
Andrew S Hansen, Bountiful, UT (US);
Inventors:
Scott B Hansen, Jupiter, FL (US);
Andrew S Hansen, Bountiful, UT (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/567 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for identifying molecules that selectively bind to a lipid binding site of a native integral membrane bound protein, includes (i) providing a solubilized integral membrane protein in a detergent micelle and having a native folding conformation; (ii) providing a soluble lipid analog that binds to the integral membrane protein at the native lipid binding site and causes a change in fluorescence of a fluorophore when bound as compared to unbound; and (iii) screening the solubilized integral membrane protein for binding to a plurality of compounds.