The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2014
Filed:
Oct. 22, 2008
Victor L. Perez, Pinecrest, FL (US);
Joe G. Hollyfield, Shaker Heights, OH (US);
Robert G. Salomon, Mayfield Village, OH (US);
Victor L. Perez, Pinecrest, FL (US);
Joe G. Hollyfield, Shaker Heights, OH (US);
Robert G. Salomon, Mayfield Village, OH (US);
The Cleveland Clinic Foundation, Cleveland, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
The invention is directed to a method of producing a non-human mammal having one or more pathological characteristics of retinal degeneration and/or age-related macular degeneration. In particular, the invention provides a method of producing a non-human mammal having age-related macular degeneration (AMD). The invention is also directed to non-human animals produced by the methods described herein. Methods of identifying an agent for use in inhibiting one or more pathological characteristics of retinal degeneration and/or AMD is also encompassed by the invention. Also provided is a method of treating AMD in an individual in need thereof comprising, administering to the individual an agent identified herein.