The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Jun. 27, 2008
Applicants:

Abhay Gaitonde, Maharashtra, IN;

Bindu Manojkumar, Maharashtra, IN;

Sandeep Sonawane, Maharashtra, IN;

Dattatrey Kokane, Maharashtra, IN;

Sandeep Mekde, Maharashtra, IN;

Dattatraya Shinde, Maharashtra, IN;

Prakash Bansode, Maharashtra, IN;

Inventors:

Abhay Gaitonde, Maharashtra, IN;

Bindu Manojkumar, Maharashtra, IN;

Sandeep Sonawane, Maharashtra, IN;

Dattatrey Kokane, Maharashtra, IN;

Sandeep Mekde, Maharashtra, IN;

Dattatraya Shinde, Maharashtra, IN;

Prakash Bansode, Maharashtra, IN;

Assignee:

Generics (UK) Limited, Hertfordshire, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to an improved process for the preparation of bosentan. In particular it relates to a process for preparing bosentan substantially free from the dimer impurity of formula (II) and the 6-hydroxy impurity of formula (III). The invention also relates to a pharmaceutical composition comprising bosentan and its use in the treatment of endothelin-receptor mediated disorders.


Find Patent Forward Citations

Loading…