The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Aug. 07, 2009
Applicants:

Andrew Guy Livingston, Knebworth, GB;

Ludmila Georgieva Peeva, London, GB;

Sheyung Wang Jerry SO, London, GB;

Renato Campos Vasconceles, London, GB;

Robin John Leatherbarrow, Horne Horley, GB;

Edward William Tate, London, GB;

Piers Robert James Gaffney, London, GB;

Inventors:

Andrew Guy Livingston, Knebworth, GB;

Ludmila Georgieva Peeva, London, GB;

Sheyung Wang Jerry So, London, GB;

Renato Campos Vasconceles, London, GB;

Robin John Leatherbarrow, Horne Horley, GB;

Edward William Tate, London, GB;

Piers Robert James Gaffney, London, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01D 61/14 (2006.01); C07H 1/06 (2006.01); C07K 1/06 (2006.01); C07K 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

According to the present invention, there is provided a process for the preparation of a first compound selected from peptides, oligonucleotides and peptide nucleic acids. The process comprises synthesizing the first compound and then separating the first compound formed in step (i) from a second compound, which is a reaction by-product of the synthesis of the first compound and/or an excess of a reagent used for the synthesis of a first compound by a process of diafiltration. The membrane used for the diafiltration process is stable in organic solvents and provides a rejection for the first compound which is greater than the rejection for the second compound.


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