The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Apr. 12, 2013
Applicant:

Complegen Partners, Llc, Seattle, WA (US);

Inventors:

Janet Ajioka, Seattle, WA (US);

Heidi S. Hummel, Seattle, WA (US);

Rich B. Meyer, San Meteo, CA (US);

John Swindle, Seattle, WA (US);

Assignee:

CompleGen Partners, LLC, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 217/90 (2006.01); C07C 323/37 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method of selectively inhibiting PKCθ in the presence of PKCδ, by administering to a subject in need thereof, a therapeutically effective amount of a compound of Formula I. The present invention also provides a method of inhibiting cytokine synthesis in a T cell, a method of inhibiting T cell proliferation, and a method of inhibiting the replication of and cytokine production by T lymphocytes, while not stimulating or inhibiting the replication of B lymphocytes.


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