The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2014
Filed:
Jan. 27, 2012
David Watt, Lexington, KY (US);
Chunming Liu, Lexington, KY (US);
Vitaliy M. Sviripa, Lexington, KY (US);
Wen Zhang, Lexington, KY (US);
David Watt, Lexington, KY (US);
Chunming Liu, Lexington, KY (US);
Vitaliy M. Sviripa, Lexington, KY (US);
Wen Zhang, Lexington, KY (US);
University of Kentucky Research Foundation, Lexington, KY (US);
Abstract
Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. Such stilbene analogs include, for example, compounds of the following formula: wherein R, R, R, R, R, Rand Rare all H; Rand Rare independently H, halo, amino, alkylamino, dialkylamino, N-oxides of dialkylamino, arylalkylamino, trialkylammonium, mercapto, alkylthio, alkanoyl, nitro, nitrosyl, cyano, alkoxy, alkenyloxy, aryl, heteroaryl, sulfonyl, sulfonamide, CONRR, NRCO(R), NRCOO(R) or NRCONRR; R, Rand R, are independently, H, alkyl, aryl, heteroaryl or a fluorine; Ris NRRZ wherein Ris H, alkyl, alkoxy, aryl or heteroaryl, Ris an alkyl group, Z is a an unshared pair of electrons, H, alkyl or oxygen; and Rand Rare halogen.