The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2014
Filed:
Aug. 30, 2006
E. Premkumar Reddy, Villanova, PA (US);
M. V. Ramana Reddy, Upper Darby, PA (US);
James F. Holland, Scarsdale, NY (US);
Lewis R. Silverman, Sleepy Hollow, NY (US);
Svetlana Zinzar, New York, NY (US);
E. Premkumar Reddy, Villanova, PA (US);
M. V. Ramana Reddy, Upper Darby, PA (US);
James F. Holland, Scarsdale, NY (US);
Lewis R. Silverman, Sleepy Hollow, NY (US);
Svetlana Zinzar, New York, NY (US);
Temple University—Of the Commonwealth System of Higher Education, Philadelphia, PA (US);
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Abstract
Methods and compositions are provided for treating myelodysplastic syndrome and acute myeloid leukemia, wherein the composition comprises at least one compound according to Formula I: wherein Ris selected from the group consisting of —NH, —NH—CH—COH, —NH—CH(CH)—COH, and —NH—C(CH)—COH, or a pharmaceutically acceptable salt of such a compound; and a DNA methyltransferase inhibitor, or a pharmaceutically acceptable salt thereof.