The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Feb. 22, 2010
Applicants:

Ping Liu, Westfield, NJ (US);

Robert J. Devita, Westfield, NJ (US);

Linus S. Lin, Westfield, NJ (US);

Marc D. Chioda, Metuchen, NJ (US);

Terence G. Hamill, Lansdale, PA (US);

Wenping LI, Lansdale, PA (US);

Inventors:

Ping Liu, Westfield, NJ (US);

Robert J. DeVita, Westfield, NJ (US);

Linus S. Lin, Westfield, NJ (US);

Marc D. Chioda, Metuchen, NJ (US);

Terence G. Hamill, Lansdale, PA (US);

Wenping Li, Lansdale, PA (US);

Assignee:

Merck Sharp & Dohme Corp, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); A61K 31/4439 (2006.01); C07D 401/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to certain Inidazole derivatives which are useful as modulators of Fatty Acid Amide Hydrolase (FAAH) and as FAAH imaging agents. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.


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