The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Dec. 16, 2009
Applicants:

Hua Xiang, Jiangsu, CN;

Tianlin Wang, Jiangsu, CN;

Hong Xiao, Jiangsu, CN;

Qidong You, Jiangsu, CN;

Yao Yao, Jiangsu, CN;

Xiaobo LI, Jiangsu, CN;

Qingjiang Liao, Jiangsu, CN;

Inventors:

Hua Xiang, Jiangsu, CN;

Tianlin Wang, Jiangsu, CN;

Hong Xiao, Jiangsu, CN;

Qidong You, Jiangsu, CN;

Yao Yao, Jiangsu, CN;

Xiaobo Li, Jiangsu, CN;

Qingjiang Liao, Jiangsu, CN;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/473 (2006.01); C07D 221/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

Indenoisoquinolinone derivatives (I), the manufacturing method and the medical use thereof, which belong to pharmaceutical chemistry and organic chemistry field, are disclosed. These compounds can be used for treating several medical symptoms related to postmenopausal syndrome, uterine fibers deterioration and aortic smooth muscle cells proliferation, especially ER-(+) depend breast cancer. Meanwhile, these compounds can also be used for treating glioma and lung cancer, and have inhibiting effect on tumor metastasis effect on tumor metastasis.


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