The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Aug. 22, 2012
Applicants:

Kunio Oshima, Osaka, JP;

Takashi Oshiyama, Osaka, JP;

Shinichi Taira, Osaka, JP;

Yasuhiro Menjo, Osaka, JP;

Hokuto Yamabe, Osaka, JP;

Shuuji Matsumura, Osaka, JP;

Masataka Ueda, Osaka, JP;

Yasuo Koga, Osaka, JP;

Kuninori Tai, Osaka, JP;

Sunao Nakayama, Osaka, JP;

Toshiyuki Onogawa, Osaka, JP;

Kenji Tsujimae, Osaka, JP;

Inventors:

Kunio Oshima, Osaka, JP;

Takashi Oshiyama, Osaka, JP;

Shinichi Taira, Osaka, JP;

Yasuhiro Menjo, Osaka, JP;

Hokuto Yamabe, Osaka, JP;

Shuuji Matsumura, Osaka, JP;

Masataka Ueda, Osaka, JP;

Yasuo Koga, Osaka, JP;

Kuninori Tai, Osaka, JP;

Sunao Nakayama, Osaka, JP;

Toshiyuki Onogawa, Osaka, JP;

Kenji Tsujimae, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 243/12 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 491/04 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a novel benzodiazepine compound that blocks the Icurrent or the Kv1.5 channel potently and more selectively than other Kchannels. The benzodiazepine compound of the invention is represented by General Formula (1) wherein R, R, R, and Rare each independently hydrogen or lower alkyl; Rand Rmay be linked to form lower alkylene; wherein Rand Rare each independently hydrogen or organic group;


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