The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2014

Filed:

Mar. 25, 2011
Applicants:

Wilfried Braje, Ludwigshafen, DE;

Katja Jantos, Ludwigshafen, DE;

Hervé Geneste, Ludwigshafen, DE;

Mario Mezler, Ludwigshafen, DE;

Margaretha Henrica Maria Bakker, Ludwigshafen, DE;

Jayne Froggett, Speyer, DE;

Inventors:

Wilfried Braje, Ludwigshafen, DE;

Katja Jantos, Ludwigshafen, DE;

Hervé Geneste, Ludwigshafen, DE;

Mario Mezler, Ludwigshafen, DE;

Margaretha Henrica Maria Bakker, Ludwigshafen, DE;

Jayne Froggett, Speyer, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/12 (2006.01); C07D 409/04 (2006.01); A61K 31/4164 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to small molecule potentiators of metabotropic receptors, in particular of the mGlu2 receptor. The present invention also relates to the use of these compounds for the prevention or treatment of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The present invention thus provides compounds of formula I and variables defined herein.


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