The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2014
Filed:
Mar. 10, 2009
Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
Leanne Berry, South San Francisco, CA (US);
Gail Lewis Phillips, San Carlos, CA (US);
Mark X. Sliwkowski, San Carlos, CA (US);
Leanne Berry, South San Francisco, CA (US);
Gail Lewis Phillips, San Carlos, CA (US);
Mark X. Sliwkowski, San Carlos, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
Combinations of the antibody-drug conjugate trastuzumab-MCC-DM1 and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting tumor cell growth, and for treating disorders such as cancer mediated by HER2 and KDR (VEGFR receptor 1). Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.