The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Feb. 03, 2011
Adrianus Petrus Antonius DE Man, Hurwenen, NL;
Johannes Bernardus Maria Rewinkel, Berghem, NL;
Christiaan Gerardus Johannes Maria Jans, Cuijk, NL;
Hans Cornelis Andreas Raaijmakers, Eindhoven, NL;
Jacobus Cornelis Henricus Maria Wijkmans, Oss, NL;
Adrianus Petrus Antonius de Man, Hurwenen, NL;
Johannes Bernardus Maria Rewinkel, Berghem, NL;
Christiaan Gerardus Johannes Maria Jans, Cuijk, NL;
Hans Cornelis Andreas Raaijmakers, Eindhoven, NL;
Jacobus Cornelis Henricus Maria Wijkmans, Oss, NL;
Merck Sharp & Dohme B.V., Haarlem, NL;
Abstract
The present invention provides 8-methyl-1-phenyl-imidazo[1,5-a]pyrazine derivatives according to formula I or pharmaceutically acceptable salts thereof. The compounds of the current invention show inhibitory activity against Lck and can be used for the treatment of Lck-mediated diseases or Lck-mediated conditions such as inflammatory disorders.