The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
May. 13, 2013
Applicant:
Dsm Ip Assets B.v., Heerlen, NL;
Inventors:
Reinhard Karge, Staufen, DE;
Jan Schultz, Lorrach, DE;
Assignee:
DSM IP Assets B.V., Heerlen, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the preparation of 5-substituted 4-amino-2-methylpyrimidines of the formula wherein R is CONHor CN, and of acid addition salts thereof, characterized in that a compound of formula HN—CH═C(R) CN (II) is reacted with acetimidic acid methyl ester or an acid addition salt thereof and that, if desired, a compound of formula I is transferred into an acid addition salt, and the transformation of a compound of formula II wherein R is CONHinto a compound of formula II wherein R is CN by treatment with POCl.