The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2014

Filed:

May. 30, 2011
Applicants:

Dino Alberico, Mississauga, CA;

Boris Gorin, Oakville, CA;

Ryan Beharrilall, Scarborough, CA;

Craig Dixon, Brooklin, CA;

Joshua Clayton, Oakville, CA;

Varghese Rexon, Brampton, CA;

Inventors:

Dino Alberico, Mississauga, CA;

Boris Gorin, Oakville, CA;

Ryan Beharrilall, Scarborough, CA;

Craig Dixon, Brooklin, CA;

Joshua Clayton, Oakville, CA;

Varghese Rexon, Brampton, CA;

Assignee:

Alphora Research Inc., Mississauga, Ontario, unknown;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 473/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Anti-virally active carbanucleosides such as entecavir are prepared by a process which utilizes, throughout the synthesis, an aromatic protectant group for the hydroxyl and the alkyl hydroxy groups of the starting material, removed as the final step of a multi-step synthesis. Such protectant groups yield intermediates which are solid and therefore easily purified at various stages of the process, for an economical and relatively fast process for synthesizing the final product.


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