The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Oct. 01, 2010
Eun Wie Cho, Daejon, KR;
Chang Kyu Heo, Daejeon, KR;
MI Kyung Woo, Daejeon, KR;
Hai Min Hwang, Daejeon, KR;
Hyang Sook Yoo, Daejeon, KR;
Jeong Heun Ko, Daejeon, KR;
Eun Wie Cho, Daejon, KR;
Chang Kyu Heo, Daejeon, KR;
Mi Kyung Woo, Daejeon, KR;
Hai Min Hwang, Daejeon, KR;
Hyang Sook Yoo, Daejeon, KR;
Jeong Heun Ko, Daejeon, KR;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to an autoantibody specifically recognizing the epitope sequence of FASN (fatty acid synthase), more particularly, to the autoantibody or a fragment comprising an antigen-binding site thereof, a diagnostic composition for hepatocellular carcinoma comprising an agent capable of assessing the expression level of the autoantibody, a hybridoma cell line producing the autoantibody, a diagnostic kit for hepatocellular carcinoma comprising the composition, a method for detecting the autoantibody of hepatocellular carcinoma patient using the composition, and a method for screening a therapeutic agent for hepatocellular carcinoma by administering candidate materials for hepatocellular carcinoma treatment to confirm a reduction in the expression level of autoantibody.