The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Nov. 05, 2010
Massimo Zampieri, Cesano Maderno, IT;
Ermes Vanotti, Milan, IT;
Paola Civaroli, Milan, IT;
Maria Gioia Fornaretto, Milan, IT;
Massimo Zampieri, Cesano Maderno, IT;
Ermes Vanotti, Milan, IT;
Paola Civaroli, Milan, IT;
Maria Gioia Fornaretto, Milan, IT;
Nerviano Medical Sciences S.r.l., Nerviano (MI), IT;
Abstract
The present invention relates to novel crystalline salts of a CDC7 or CDC7/CDKs inhibitor, to a novel crystal form of the corresponding free base, to a process for their preparation, to hydrates, solvates and polymorphs of such new salt forms, to their use in therapy and to pharmaceutical compositions containing them. Such crystal salts are selected from L-asparate, hemifumarate, hydrochloride, maleate, mesylate, sulfate, L-tartrate or phosphate salts of 5-(2-amino-pyrimidin-4-yl)-2-(2,4-dichloro-phenyl)-1H-pyrrole-3-carboxylic acid amide.