The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8658659 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 25, 2014

Filed:

Jan. 05, 2012
Applicants:

David Grierson, Versailles, FR;

Abdellah Benjahad, Champigny sur Marne, FR;

Alain Moussy, Paris, FR;

Martine Croisy, Cernay la Ville, FR;

Inventors:

David Grierson, Versailles, FR;

Abdellah Benjahad, Champigny sur Marne, FR;

Alain Moussy, Paris, FR;

Martine Croisy, Cernay la Ville, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/46 (2006.01); C07D 263/58 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel compounds selected from substituted oxazole derivatives of formula (I) that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit, bcr-abl and Flt-3 inhibitors.


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