The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Sep. 20, 2010
Applicants:
Hugh Y. Zhu, Warren, NJ (US);
Jagdish A. Desai, Monroe Township, NJ (US);
Alan B. Cooper, West Caldwell, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Inventors:
Hugh Y. Zhu, Warren, NJ (US);
Jagdish A. Desai, Monroe Township, NJ (US);
Alan B. Cooper, West Caldwell, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); C07D 401/14 (2006.01); C07D 211/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are the ERK inhibitors of formula 1.0: (Formula (A1)), and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine ring that can have a bridge or a fused ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula A1.