The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2014

Filed:

Jul. 30, 2009
Applicants:

Hiromi Kumon, Okayama, JP;

Yasutomo Nasu, Okayama, JP;

Yuji Kashiwakura, Okayama, JP;

Masami Watanabe, Okayama, JP;

Nam-ho Huh, Okayama, JP;

Masakiyo Sakaguchi, Okayama, JP;

Inventors:

Hiromi Kumon, Okayama, JP;

Yasutomo Nasu, Okayama, JP;

Yuji Kashiwakura, Okayama, JP;

Masami Watanabe, Okayama, JP;

Nam-ho Huh, Okayama, JP;

Masakiyo Sakaguchi, Okayama, JP;

Assignees:

National University Corporation Okayama University, Okayama-shi, Okayama, JP;

Momotaro-Gene Inc., Okayama-shi, Okayama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); C12N 15/00 (2006.01); C12N 15/63 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for potentiating the antitumor immunity in an animal by administering REIC/Dkk-3, or a therapeutic agent for malignant mesothelioma containing REIC/Dkk-3, or a vector containing the DNA as an active ingredient; wherein the DNA consists of the nucleotide sequence shown in SEQ ID NO: 1; or (b) a DNA hybridizing under stringent conditions to the DNA consisting of a nucleotide sequence complementary to the nucleotide sequence shown in SEQ ID NO: 1 and encoding a protein having apoptosis-inducing activity and interleukin (IL-7) production-accelerating activity in cells.


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