The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Mar. 13, 2012
Tom Albert, Verona, WI (US);
Todd Richmond, Madison, WI (US);
Matthew Rodesch, Stoughton, WI (US);
Klaus-peter Stengele, Pleiskirchen, DE;
Jochen Bühler, Waldkraiburg, DE;
Tom Albert, Verona, WI (US);
Todd Richmond, Madison, WI (US);
Matthew Rodesch, Stoughton, WI (US);
Klaus-Peter Stengele, Pleiskirchen, DE;
Jochen Bühler, Waldkraiburg, DE;
Roche NimbleGen, Inc., Madison, WI (US);
Abstract
The present invention relates to a microarray comprising at least 50,000 oligopeptide features per cmwhere the oligopeptide features represent at least 50%, 60%, 70%, 80%, 90%, 95%, 99%, or 100% of the proteome of a virus or an organism. The present invention further relates to methods for the synthesis of such microarrays and methods of using microarrays comprising at least 50,000 oligopeptide features per cm. In an embodiment of the invention, the oligopeptide features represent proteins expressed in the same species, wherein the oligopeptide features are presented in a tiling pattern representing at least about 5,000 to-at least about 25,000 proteins expressed in a species. In some embodiments, the oligopeptide microarray features represent proteins expressed in the same species, wherein the microarray features are present in a tiling pattern that represents at least about 5,000 to at least about 50,000 expressed proteins.