The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
May. 26, 2009
Bennard Van Ravenzwaay, Altrip, DE;
Werner Mellert, Haβloch, DE;
Eric Fabian, Ludwigshafen, DE;
Volker Strauss, Bad Dürkheim, DE;
Tilmann B. Walk, Kleinmachnow, DE;
Ralf Looser, Berlin, DE;
Edgar Leibold, Carlsberg, DE;
Hennicke Kamp, Bischheim, DE;
Georgia Coelho Palermo Cunha, Sao Paulo, BR;
Michael Manfred Herold, Berlin, DE;
Jan C Wiemer, Berlin, DE;
Alexandre Prokoudine, Berlin, DE;
Bennard van Ravenzwaay, Altrip, DE;
Werner Mellert, Haβloch, DE;
Eric Fabian, Ludwigshafen, DE;
Volker Strauss, Bad Dürkheim, DE;
Tilmann B. Walk, Kleinmachnow, DE;
Ralf Looser, Berlin, DE;
Edgar Leibold, Carlsberg, DE;
Hennicke Kamp, Bischheim, DE;
Georgia Coelho Palermo Cunha, Sao Paulo, BR;
Michael Manfred Herold, Berlin, DE;
Jan C Wiemer, Berlin, DE;
Alexandre Prokoudine, Berlin, DE;
BASF SE, Ludwigshafen, DE;
Abstract
The present invention pertains to the field of toxicological assessments of risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal proliferation. It also relates to a method of determining whether a compound is capable of inducing such peroxisomal proliferation in a subject and to a method of identifying a drug for treating increased peroxisomal proliferation. Furthermore, the present invention relates to a data collection of characteristic values of at least five metabolites, a data storage medium for the data collection, and a system and a device for diagnosing increased peroxisomal proliferation. Finally, the present invention pertains to the use of a group of metabolites or means for the determination thereof for the manufacture of a diagnostic device or composition for diagnosing increased peroxisomal proliferation in a subject.