The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2014

Filed:

Dec. 16, 2009
Applicants:

Nina Schneider, Offenburg, DE;

Hans Wolfgang Höffken, Ludwigshafen, DE;

Inventors:

Nina Schneider, Offenburg, DE;

Hans Wolfgang Höffken, Ludwigshafen, DE;

Assignee:

BASF SE, Ludwigshafen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/00 (2006.01); C12P 7/02 (2006.01); C12N 9/04 (2006.01); C12N 1/20 (2006.01); C12P 21/06 (2006.01); C12N 15/00 (2006.01); C07D 333/12 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel phenylethanol dehydrogenase mutants, to a method for the manufacture thereof; to coded nucleic acid sequences therefor, to expression cassettes, to vectors and recombinant microorganisms that contain said sequences; to a method for the biocatalytic synthesis of substituted, optically active alcohols and to the use of said mutants; and particularly to a method for manufacturing duloxetine alcohol or duloxetine, comprising a synthesis step catalyzed biocatalytic by said mutants.


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