The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Feb. 24, 2012
Baoguo Zhu, Guangdong, CN;
Desheng Tao, Guangdong, CN;
Bill Nai-chau Sun, Shanghai, CN;
Lee-hwei King Sun, Shanghai, CN;
Ruey Shyan Liou, Shanghai, CN;
Cecily Rou-yun Sun, Shanghai, CN;
Qiang LI, Shanghai, CN;
Yucai Peng, Guangdong, CN;
Jingwei Zhang, Guangdong, CN;
Zhenxiang HU, Guangdong, CN;
Baoguo Zhu, Guangdong, CN;
Desheng Tao, Guangdong, CN;
Bill Nai-Chau Sun, Shanghai, CN;
Lee-Hwei King Sun, Shanghai, CN;
Ruey Shyan Liou, Shanghai, CN;
Cecily Rou-Yun Sun, Shanghai, CN;
Qiang Li, Shanghai, CN;
Yucai Peng, Guangdong, CN;
Jingwei Zhang, Guangdong, CN;
Zhenxiang Hu, Guangdong, CN;
Livzon Mabpharm Inc., Zhuhai, Guangdong, CN;
Abstract
The present invention provides a humanized anti-TNF monoclonal antibody and the use thereof. The humanized anti-TNF monoclonal antibody significantly reduces the immunogenicity of murine-antibody while retaining the ability of antibody to recognize antigen, compared with conservative mouse chimeric antibody. Therefore, safety of the antibody in clinical applications has been improved.