The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Apr. 08, 2013
Applicant:
Aeras Global Tb Vaccine Foundation, Bethesda, MD (US);
Inventors:
Jerald C. Sadoff, Washington, DC (US);
Mohamad F. Jamiluddin, Frederick, MD (US);
Ravi P. Anantha, Gaithersburg, MD (US);
John F. Fulkerson, Jr., Silver Springs, MD (US);
Assignee:
Aeras Global TB Vaccine Foundation, Bethesda, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 39/02 (2006.01); A61K 39/112 (2006.01);
U.S. Cl.
CPC ...
Abstract
Bacterial delivery systems with improved transgene expression are provided. The recombinant bacterial delivery systems deliver transgenes of interest and suppressors of the eukaryotic Type I interferon response to eukaryotic cells. Suppression of the eukaryotic Type I interferon response allows improved expression of the encoded transgene.