The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Mar. 06, 2012
Daniel Mueth, Chicago, IL (US);
Joseph Plewa, Park Ridge, IL (US);
Jessica Shireman, Kansas City, MO (US);
Amy Anderson, Palatine, IL (US);
Lewis Gruber, Chicago, IL (US);
Neil Harris Rosenbaum, Chicago, IL (US);
Daniel Mueth, Chicago, IL (US);
Joseph Plewa, Park Ridge, IL (US);
Jessica Shireman, Kansas City, MO (US);
Amy Anderson, Palatine, IL (US);
Lewis Gruber, Chicago, IL (US);
Neil Harris Rosenbaum, Chicago, IL (US);
Premium Genetics (UK) Limited, Cheshire, GB;
Abstract
The invention provides a method, apparatus and system for separating cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One exemplary method includes providing a first flow having a plurality of components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first cellular component of the plurality of components into the second flow while concurrently maintaining a second cellular component of the plurality of components in the first flow. The second flow having the first cellular component is then differentially removed from the first flow having the second cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.