The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Jun. 04, 2012
Seth Bjork, Sodertalje, SE;
Vern Delisser, Sodertalje, SE;
Peter Johnstrom, Sodertalje, SE;
Nils Anders Nilsson, Sodertalje, SE;
Katinka Ruda, Sodertalje, SE;
Per Magnus Schou, Sodertalje, SE;
Britt-marie Swahn, Sodertalje, SE;
Seth Bjork, Sodertalje, SE;
Vern Delisser, Sodertalje, SE;
Peter Johnstrom, Sodertalje, SE;
Nils Anders Nilsson, Sodertalje, SE;
Katinka Ruda, Sodertalje, SE;
Per Magnus Schou, Sodertalje, SE;
Britt-Marie Swahn, Sodertalje, SE;
AstraZeneca AB, Södertälje, SE;
Abstract
The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form.