The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Oct. 18, 2007
Applicants:
Audra L. Stinchcomb, Lexington, KY (US);
Peter A. Crooks, Nicholasville, KY (US);
Mohamed O. Hamad, Lexington, KY (US);
Paul K. Kiptoo, Lexington, KY (US);
Inventors:
Audra L. Stinchcomb, Lexington, KY (US);
Peter A. Crooks, Nicholasville, KY (US);
Mohamed O. Hamad, Lexington, KY (US);
Paul K. Kiptoo, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/00 (2006.01); C07D 489/02 (2006.01); C07D 489/12 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is directed to novel codrugs comprising bupropion or hydroxybupropion and an opioid antagonist or an opioid agonist joined together by chemical bonding. The codrugs provide a significant increase in the transdermal flux across human skin, as compared to the basic opioid antagonist or opioid agonist.