The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Apr. 26, 2012
Vinayak Gore, Hyderabad, IN;
Choudhari Bharati, Hyderabad, IN;
Mahesh Hublikar, Hyderabad, IN;
Prakash Bansode, Hyderabad, IN;
Sandip Sinore, Hyderabad, IN;
Vinayak Gore, Hyderabad, IN;
Choudhari Bharati, Hyderabad, IN;
Mahesh Hublikar, Hyderabad, IN;
Prakash Bansode, Hyderabad, IN;
Sandip Sinore, Hyderabad, IN;
Mylan Laboratories Limited, Hyderabad, IN;
Abstract
A novel process for the preparation of Etravirine comprises the condensing of ethyl cyanoacetate with N-cyanophenylguanidine to obtain an —OH compound of formula (II), which is further converted to a leaving group of formula (III). The compound of formula (III) is optionally protected and brominated to yield compound of formula (IV). The condensation of formula (IV) with 3,5-dimethyl-4-hydroxybenzonitrile yields a compound of formula (VI), and an optional deprotection of the compound of formula (VI) results in Etravirine.