The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Feb. 06, 2008
Applicants:
Uwe Heinelt, Weisbaden, DE;
Hans-jochen Lang, Hofheim, DE;
Inventors:
Uwe Heinelt, Weisbaden, DE;
Hans-Jochen Lang, Hofheim, DE;
Assignee:
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/50 (2006.01); C07D 235/20 (2006.01); C07D 235/04 (2006.01); C07D 235/02 (2006.01); C07D 263/28 (2006.01); C07D 263/58 (2006.01); C07D 263/52 (2006.01); C07D 265/08 (2006.01); C07D 265/06 (2006.01); C07D 265/12 (2006.01); C07D 265/18 (2006.01); C07D 277/18 (2006.01); C07D 277/08 (2006.01); C07D 409/12 (2006.01); C07D 409/02 (2006.01); C07D 413/12 (2006.01); C07D 495/04 (2006.01); C07D 233/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides the process illustrated in scheme 1 for synthesizing heterocyclic compounds of formula I. In the process, an isothiocyanate of formula II is initially reacted with a primary amine or formula III to give a thiourea of formula IV. Subsequently, the thiourea of formula IV is converted to the corresponding heterocycle of formula I using a base and a sulfonyl chloride.