The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2014

Filed:

Aug. 21, 2009
Applicants:

Guohan Yang, Mansfield, MA (US);

Ton That Hai, Round Lake, IL (US);

Bennett P. Melnick, Chicago, IL (US);

Paul Sanders, Greendale, WI (US);

Cong Jiang, Gurnee, IL (US);

Catherine Quinn, Mundelein, IL (US);

Jie LI, Cary, NC (US);

Arounaguiry Ambroise, Cary, NC (US);

Larry R. Brown, Newton, MA (US);

Inventors:

Guohan Yang, Mansfield, MA (US);

Ton That Hai, Round Lake, IL (US);

Bennett P. Melnick, Chicago, IL (US);

Paul Sanders, Greendale, WI (US);

Cong Jiang, Gurnee, IL (US);

Catherine Quinn, Mundelein, IL (US);

Jie Li, Cary, NC (US);

Arounaguiry Ambroise, Cary, NC (US);

Larry R. Brown, Newton, MA (US);

Assignees:

Baxter Healthcare S.A., Glattpark (Opfikon), CH;

Baxter International Inc., Deefield, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/46 (2006.01); C07C 271/08 (2006.01); C07C 69/63 (2006.01); C07C 69/66 (2006.01); A61K 31/27 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to polymeric derivatives, which can be conjugated to an amino-containing drug to improve its in vivo properties. The polymeric derivative can subsequently be released to yield the drug in its native form. Methods of preparing and using these polymeric derivatives and drug conjugates are described.


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