The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Mar. 05, 2010
Hiroshi Yoshida, Osaka, JP;
Keisuke Tonogaki, Osaka, JP;
Masahiro Sakagami, Osaka, JP;
Kenji Takaya, Osaka, JP;
Hiroshi Yoshida, Osaka, JP;
Keisuke Tonogaki, Osaka, JP;
Masahiro Sakagami, Osaka, JP;
Kenji Takaya, Osaka, JP;
Shionogi Co., Ltd., Osaka-shi, JP;
Abstract
The present invention discloses novel cyclohexane derivatives having NPY Y5 receptor antagonistic activity. Specifically, the present invention discloses a compound represented by the formula (I), or a pharmaceutically acceptable salt or a solvate thereof: wherein A is substituted or unsubstituted aryl or heterocyclyl; a combination of X and Y is a combination selected from (X, Y)═(C(═O)N(R), C(═O)N(R)), (C(═O)N(R), imidazole-1,3-diyl), (N(R), C(═O)N(R)), (O, C(═O)N(R)), (C(R)(R), N(R)) or (a single bond, C(═O)N(R)); R, Rand Rare independently hydrogen or substituted or unsubstituted alkyl; Ris substituted or unsubstituted aryl or heterocyclyl; Ris halogen, oxo, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryloxy; m is 0 or 1; and n is an integer of 0 to 5; and B is aromatic carbocycle, monocyclic heterocycle or fused bicyclic heterocycle.