The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2014

Filed:

Mar. 31, 2009
Applicants:

Michael Ochse, Ludwigshafen, DE;

Udo Lange, Mannheim, DE;

Wilfried Braje, Ludwigshafen, DE;

Berthold Behl, Ludwigshafen, DE;

Wilfried Hornberger, Ludwigshafen, DE;

Mario Mezler, Ludwigshafen, DE;

Wilhelm Amberg, Ludwigshafen, DE;

Charles W. Hutchins, Green Oaks, IL (US);

Inventors:

Michael Ochse, Ludwigshafen, DE;

Udo Lange, Mannheim, DE;

Wilfried Braje, Ludwigshafen, DE;

Berthold Behl, Ludwigshafen, DE;

Wilfried Hornberger, Ludwigshafen, DE;

Mario Mezler, Ludwigshafen, DE;

Wilhelm Amberg, Ludwigshafen, DE;

Charles W. Hutchins, Green Oaks, IL (US);

Assignees:

AbbVie Inc., North Chicago, IL (US);

AbbVie Deutschland GmbH & Co. KG, Wiesbaden, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/00 (2006.01); A61K 31/472 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to tetrahydroisoquinoline of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroisoquinolines for therapeutic purposes. The tetrahydroisoquinolines are GlyT1 inhibitors.


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