The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2014

Filed:

Feb. 08, 2012
Applicants:

Robert Heald, Harlow, GB;

Stephen Price, Harlow, GB;

Brian Safina, South San Francisco, CA (US);

Pascal Pierre Alexandre Savy, Harlow, GB;

Eileen Mary Seward, Harlow, GB;

Daniel P. Sutherlin, Burlingame, CA (US);

Bohdan Waszkowycz, Harlow, GB;

Inventors:

Robert Heald, Harlow, GB;

Stephen Price, Harlow, GB;

Brian Safina, South San Francisco, CA (US);

Pascal Pierre Alexandre Savy, Harlow, GB;

Eileen Mary Seward, Harlow, GB;

Daniel P. Sutherlin, Burlingame, CA (US);

Bohdan Waszkowycz, Harlow, GB;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); C07D 473/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.


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