The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2014

Filed:

Aug. 18, 2008
Applicants:

Tesfaye Biftu, Freehold, NJ (US);

Danqing Feng, Green Brook, NJ (US);

Ann E. Weber, Scotch Plains, NJ (US);

Jason M. Cox, East Windsor, NJ (US);

Xiaoxia Qian, New York, NY (US);

Jinyou Xu, Scotch Plains, NJ (US);

Inventors:

Tesfaye Biftu, Freehold, NJ (US);

Danqing Feng, Green Brook, NJ (US);

Ann E. Weber, Scotch Plains, NJ (US);

Jason M. Cox, East Windsor, NJ (US);

Xiaoxia Qian, New York, NY (US);

Jinyou Xu, Scotch Plains, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/33 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to substituted six-membered heterocyclic compounds of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as obesity and diabetes, particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.


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