The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Mar. 17, 2009
Karsten Hipler, Basel, CH;
Andrew Miller, London, GB;
Jaroslav Turanek, Brno, CZ;
Miroslav Ledvina, Prague, CZ;
Karsten Hipler, Basel, CH;
Andrew Miller, London, GB;
Jaroslav Turanek, Brno, CZ;
Miroslav Ledvina, Prague, CZ;
Imuthes Limited, London, GB;
Institute of Organic Chemistry and Biochemistry AV CR, V.V.I., Prague, CZ;
Abstract
The invention provides a compound (which can act as an adjuvant) of Formula I or Formula (II), wherein RRRRand Rare each independently selected from hydrogen, acetyl, hydrocarbyl, a lipid moiety and a lipid acyl moiety; Ris a hydroxyl, a hydrocarbyl, a lipid moiety, a lipid acyl moiety; or an amino hydrocarbyl group optionally substituted with a hydrocarbyl, a lipid moiety or a lipid acyl moiety; Rand Rare each independently selected from acetyl, a hydrocarbyl, a lipid moiety and a lipid acyl moiety; X is a peptide chain; The above normuramylglycopeptide compounds can be located in liposomes and micelles and can function as immunomodulators, along with a desired antigen (or DNA encloding the antigen), in (e.g. DNA) vaccines.