The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Nov. 27, 2009
Alexandra Krog, Bodenheim Nackenheim, DE;
Jochen Kruip, Erzhausen, DE;
Paulus Wohlfart, Bensheim, DE;
Johann Gassenhuber, Wiesbaden, DE;
Kathrin Heermeier, Hochheim, DE;
Hartmut Strobel, Liederbach, DE;
Natalie Karst, Paris, FR;
Alexandra Ferrier, Paris, FR;
Christian Viskov, Ris Orangis, FR;
Alexandra Krog, Bodenheim Nackenheim, DE;
Jochen Kruip, Erzhausen, DE;
Paulus Wohlfart, Bensheim, DE;
Johann Gassenhuber, Wiesbaden, DE;
Kathrin Heermeier, Hochheim, DE;
Hartmut Strobel, Liederbach, DE;
Natalie Karst, Paris, FR;
Alexandra Ferrier, Paris, FR;
Christian Viskov, Ris Orangis, FR;
Sanofi, Paris, FR;
Abstract
The present invention relates to a method of screening for a modulator of endothelial NO synthase (eNOS) expression, a method of diagnosing a cardiovascular disease in a subject, the use of HEBP-1 for the identification of a medicament for preventing and/or treating a disease involving eNOS dysfunction, particularly a cardiovascular disease, the use of HEBP-1 for the detection of a component of eNOS signal transduction, and the use of HEBP1 for the regulation of eNOS promoter activity.