The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Mar. 15, 2013
Hong Kong Baptist University, Kowloon, HK;
Zhaoxiang Bian, Hong Kong, HK;
Siu Wai Tsang, Hong Kong, HK;
Aiping Lu, Hong Kong, HK;
Haitao Xiao, Hong Kong, HK;
Hongyan Qin, Hong Kong, HK;
Albert Sun-Chi Chan, Hong Kong, HK;
Hongxi Xu, Hong Kong, HK;
Shilin Chen, Hong Kong, HK;
Dajian Yang, Hong Kong, HK;
Hong Kong Baptist University, Kowloon Tong, Kowloon, HK;
Abstract
The present invention relates to a method of using an anthraquinone derivative namely 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, or known as Rhein, for treating chronic pancreatitis induced fibrosis of the pancreas. More particularly, the present invention relates to a method of using Rhein, its derivatives and/or chemical variants as an anti-fibrotic agent. The present invention particularly relates to the suppression of pancreatic stellate cell activation for the management of chronic inflammatory, fibrotic and tumorigenic pathologies in the pancreas.