The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Jun. 20, 2011
Irun R. Cohen, Rehovot, IL;
Bracha Rager-zisman, Beer Sheva, IL;
Angel Porgador, Lehavim, IL;
Johannes Herkel, Hamburg, DE;
Irun R. Cohen, Rehovot, IL;
Bracha Rager-Zisman, Beer Sheva, IL;
Angel Porgador, Lehavim, IL;
Johannes Herkel, Hamburg, DE;
Yeda Research and Development Co. Ltd., Rehovot, IL;
B.G. Negev Technologies and Applications Ltd., Beer Sheva, IL;
Abstract
The present invention provides improved vaccines comprising an isolated viral antigenic peptide and a synthetic peptide derived from a T cell epitope of HSP60. The invention includes mixtures where the peptide serves as an adjuvant as well as conjugates where the peptide is covalently linked to the viral antigen. The known synthetic peptide carrier, p458, provides significantly improved immunogenicity for synthetic viral epitopes and analogs. Ec27 is a novel peptide derived from HSP60 which increases the immunogenicity substantially of the viral antigen both as a mixture or a covalent conjugate. Some of the isolated viral epitopes are novel and are claimed for diagnostic as well as therapeutic or prophylactic uses.