The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2014
Filed:
Apr. 16, 2008
Vinayak G. Gore, Maharashtra, IN;
Avinash C. Gaikwad, Maharashtra, IN;
Maheshkumar Gadakar, Maharashtra, IN;
Vinay Kumar Shukla, Maharashtra, IN;
Vinayak G. Gore, Maharashtra, IN;
Avinash C. Gaikwad, Maharashtra, IN;
Maheshkumar Gadakar, Maharashtra, IN;
Vinay Kumar Shukla, Maharashtra, IN;
Generics [UK] Limited, , GB;
Abstract
The present invention relates to processes for the preparation of 4-hydroxy-α'-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthoate (salmeterol xinafoate) (12a), the preparation of 4-hydroxy-α′-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (salmeterol) (11), the preparation of protected N-[6-(4-phenylbutoxy)hexyl]amine intermediates (7), and the preparation of 6-substituted (4-phenylbutoxy)hexane intermediates (5), shown below, wherein X is a leaving group and Pg is a protecting group.