The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2014
Filed:
Oct. 13, 2009
Sung Wuk Kim, Seongnam-si, KR;
Sung Soo Jun, Seongnam-si, KR;
Hyae Gyeong Cheon, Daejeon-si, KR;
Kwang Rok Kim, Daejeon-si, KR;
Sang Dal Rhee, Daejeon-si, KR;
Won Hoon Jung, Daejeon-si, KR;
Jong Cheol Lee, Daejeon-si, KR;
Sung Wuk Kim, Seongnam-si, KR;
Sung Soo Jun, Seongnam-si, KR;
Hyae Gyeong Cheon, Daejeon-si, KR;
Kwang Rok Kim, Daejeon-si, KR;
Sang Dal Rhee, Daejeon-si, KR;
Won Hoon Jung, Daejeon-si, KR;
Jong Cheol Lee, Daejeon-si, KR;
Hanall Biopharma Co., Ltd., Daejeon-Si, KR;
Korea Research Institute of Chemical Technology, Daejeon-Si, KR;
Abstract
The present invention provides an N1-2-thiophen-2-ylethyl-N2-substituted biguanide derivative of formula (I) or a pharmaceutically acceptable salt thereof, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. The inventive N1-2-thiophen-2-ylethyl-N2-substituted biguanide derivative exhibits improved blood glucose level- and lipid level-lowering effects even with a reduced dosage as compared to conventional drugs, and thus, it is useful for preventing or treating diabetes, metabolic syndromes such as insulin-independent diabetes, obesity and atherosclerosis, or a P53 gene defect-related cancer.