The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2014

Filed:

Jul. 22, 2010
Applicants:

Massimo Zampieri, Cesano Maderno, IT;

Italo Beria, Nerviano, IT;

Annalisa Airoldi, Nosate, IT;

Ilaria Candiani, Busto Arsizio, IT;

Riccardo Frigerio, Sovico, IT;

Inventors:

Massimo Zampieri, Cesano Maderno, IT;

Italo Beria, Nerviano, IT;

Annalisa Airoldi, Nosate, IT;

Ilaria Candiani, Busto Arsizio, IT;

Riccardo Frigerio, Sovico, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 491/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel crystalline, water-soluble salts of a plk inhibitor. Such crystal salts are for example L-tartrate, succinate, phosphate, mesylate, maleate, L-malate, hydrochloride, fumarate (half mole of counterion), fumarate, citrate (half mole of counterion), benzenesulfonate and L-aspartate (half mole of counterion). New crystal forms of the base as well as solvates and hydrates of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.


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