The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2014

Filed:

Mar. 12, 2009
Applicants:

Francisco Villarreal, Chula Vista, CA (US);

Katrina Go Yamazaki, La Jolla, CA (US);

Pam Rajendran Taub, San Diego, CA (US);

Alan Maisel, Solana Beach, CA (US);

Inventors:

Francisco Villarreal, Chula Vista, CA (US);

Katrina Go Yamazaki, La Jolla, CA (US);

Pam Rajendran Taub, San Diego, CA (US);

Alan Maisel, Solana Beach, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/65 (2006.01);
U.S. Cl.
CPC ...
Abstract

The disclosure provides a method of reducing infarct size in the heart following permanent ischemia or ischemia/reperfusion (IR) event or method for delaying, attenuating or preventing adverse cardiac remodeling comprising administering a drug selected from the group consisting of epicatechin, derivatives thereof and pharmaceutically acceptable salts thereof, wherein the subject is a human or a veterinary animal. Additionally the disclosure provides a method of treating subarachnoid hemorrhage or atrial fibrillation or of enhancing or preserving migration, seeding, proliferation, differentiation and/or survival of stem cells in injured heart tissue comprising administering a drug selected from the group consisting of epicatechin, derivatives thereof and pharmaceutically acceptable salts thereof. The effects of epicatechin administration are sustained over time.


Find Patent Forward Citations

Loading…