The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2014
Filed:
Dec. 28, 2011
Bryan P. Toole, Mt. Pleasant, SC (US);
Suniti Misra, Mt. Pleasant, SC (US);
Shibnath Ghatak, Mt. Pleasant, SC (US);
Bryan P. Toole, Mt. Pleasant, SC (US);
Suniti Misra, Mt. Pleasant, SC (US);
Shibnath Ghatak, Mt. Pleasant, SC (US);
Tufts University, Boston, MA (US);
Abstract
Pharmaceutical compositions and methods for sensitizing multi-drug resistant cancer or radiation resistant cancer cells to chemotherapeutic agents are provided. Compositions include ligands of hyaluronan receptors, including glycosaminoglycans such as hyaluronan oligomers and derivatives of these oligomers, hyaluronan binding proteins, antibodies specific for hyaluronan receptors, hyaluronan mimetics, inhibitors of hyaluronan synthesis, and stimulators of hyaluronan degradation.