The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2014
Filed:
Aug. 18, 2008
Applicants:
Beatriz Llano-sotelo, Prospect Heights, IL (US);
Alexander S. Mankin, River Forest, IL (US);
Dorota Klepacki, Chicago, IL (US);
Inventors:
Beatriz Llano-Sotelo, Prospect Heights, IL (US);
Alexander S. Mankin, River Forest, IL (US);
Dorota Klepacki, Chicago, IL (US);
Assignee:
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention discloses compositions of peptide inhibitors of protein synthesis, and methods of identifying peptide inhibitors that are capable of inhibiting protein synthesis through an interaction at a stem-loop H18 in 16S rRNA of a 30S ribosomal subunit. Screening methods for peptides are disclosed, in addition to methods of determining the affinity of a test compound for a ribosomal subunit.