The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2014
Filed:
May. 06, 2008
Andreas Bergmann, Berlin, DE;
Jana Papassotiriou, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils Morgenthaler, Berlin, DE;
Stefan Anker, Berlin, DE;
Andreas Bergmann, Berlin, DE;
Jana Papassotiriou, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils Morgenthaler, Berlin, DE;
Stefan Anker, Berlin, DE;
B.R.A.H.M.S. GmbH, Henningsdorf, DE;
Abstract
The present invention relates to an in vitro method for medical diagnosis, prognosis and therapy follow-up for patients having a cardiac disease or being suspected of developing or having a cardiac disease comprising the steps of: providing a sample of a patient having a cardiac disease or being suspected of developing or having a cardiac disease, determining amino-terminal proANp or partial peptides thereof having from 12 to 98 amino acids in said sample using at least one antibody that binds specifically to a partial sequence of amino-terminal proANP, attributing the determined amino-terminal proANP level or the level of partial peptides thereof to a clinical picture wherein the attribution is carried out independent of the BMI of the patient. The present invention further concerns a rapid test assay and a kit for conducting the method of the present invention and the use of antibodies suitable for the method and assays according to the present invention.